DESIGNING MRNA- AND PEPTIDE-BASED VACCINE CONSTRUCT AGAINST EMERGING MULTIDRUG-RESISTANT CITROBACTER FREUNDII: A COMPUTATIONAL-BASED SUBTRACTIVE PROTEOMICS APPROACH

Background and Objectives: Citrobacter freundii (C.freundii) is an emerging and opportunistic Gram-negative bacteria of the human gastrointestinal tract associated with nosocomial and severe respiratory tract infections.It has also been associated with pneumonia, bloodstream, and urinary tract infections.Intrinsic and adaptive virulence characteris

Background To assess the effect of policies supporting local medicine production to improve access to medicines.Methods We adapted the WHO/HAI instruments measuring medicines availability and prices to differentiate local from imported products, then pilot tested in Ethiopia and Tanzania.In each outlet, prices were recorded for all products in stoc

Abstract The southern Meleiha concession, situated within the development encouragement areas of the Agiba Petroleum Company between Matrouh Basin and Shushan basin, spans approximately 700 km2.This study examined late Cretaceous strata to improve trap identification in the Bahariya, Alamein Dolomite, and Alam El Bueib Members.This required a thoro